YhhN-like (IPR012506)

Short name: YhhN

Overlapping homologous superfamilies


Family relationships



The members of this family are similar to the hypothetical protein yhhN expressed by E. coli (P0ADI9). Many are annotated as possible transmembrane proteins, and in fact they all have a high proportion of hydrophobic residues. A human member of this family, formerly known as TMEM86B, is a lysoplasmalogenase that catalyzes the hydrolysis of the vinyl ether bond of lysoplasmalogen [PMID: 21515882]. Putative conserved active site residues have been proposed for the YhhN family [PMID: 26335199].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.