TadE-like (IPR012495)

Short name: TadE

Overlapping homologous superfamilies


Family relationships



The members of this family are similar to a region of the protein product of the bacterial tadE locus (Q9S4A6). In various bacterial species, the tad locus is closely linked to flp-like genes, which encode proteins required for the production of pili involved in adherence to surfaces [PMID: 11553455]. It is thought that the tad loci encode proteins that act to assemble or export an Flp pilus in various bacteria [PMID: 11553455]. All tad loci but TadA have putative transmembrane regions [PMID: 11553455], and in fact the region in question is this family has a high proportion of hydrophobic amino acid residues.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.