Domain

DmpG-like communication (IPR012425)

Short name: DmpG_comm

Domain relationships

None.

Description

This domain is found towards the C-terminal region of various aldolase enzymes. It consists of five alpha-helices, four of which form an antiparallel helical bundle that plugs the C terminus of the N-terminal TIM barrel domain [PMID: 12764229]. The communication domain is thought to play an important role in the heterodimerisation of the enzyme [PMID: 12764229].

Members of this entry heterodimerise with members of IPR003361 to form a bifunctional aldolase-dehydrogenase [PMID: 12764229].

GO terms

Biological Process

GO:0019439 aromatic compound catabolic process

Molecular Function

GO:0016833 oxo-acid-lyase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom