Family

Chromatin modification-related protein Eaf7/MRGBP (IPR012423)

Short name: Eaf7/MRGBP

Family relationships

None.

Description

This entry includes fungal chromatin modification-related protein Eaf7 and its mammalian homologue, MRG/MORF4L-binding protein (MRGBP). Eaf7/MRGBP is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A [PMID: 15353583].

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0043189 H4/H2A histone acetyltransferase complex
GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER