Thiamine triphosphatase (IPR012177)

Short name: ThTPase

Overlapping homologous superfamilies

Family relationships



Thiamine triphosphate (ThTP), the triphosphorylated form of vitamin B1, is found in most organisms including bacteria, fungi, plants and animals. In mammals, cytosolic ThTP concentration is kept low by a highly specific soluble phosphohydrolase, the 25 kDa thiamine triphosphatase (ThTPase) [PMID: 23707715].

This entry includes the 25 kDa thiamine triphosphatase (ThTPase) and its homologues mostly from mammals.

GO terms

Biological Process

GO:0006772 thiamine metabolic process

Molecular Function

GO:0050333 thiamin-triphosphatase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.