Thiamine pyrophosphate enzyme, central domain (IPR012000)

Short name: Thiamin_PyroP_enz_cen_dom

Overlapping homologous superfamilies

Domain relationships



A number of enzymes require thiamine pyrophosphate (TPP) (vitamin B1) as a cofactor. It has been shown [PMID: 8604141] that some of these enzymes are structurally related. This central domain of TPP enzymes contains a 2-fold Rossman fold.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0000287 magnesium ion binding
GO:0030976 thiamine pyrophosphate binding

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.