HAD-superfamily hydrolase, subfamily IA, CTE7 (IPR011950)

Short name: HAD-SF_hydro_IA_CTE7

Overlapping homologous superfamilies

Family relationships


This family of sequences from archaea and metazoans includes N-acylneuraminate-9-phosphatase Nanp from metazoa [PMID: 16237198] and glyceraldehyde 3-phosphate phosphatases from archaea [PMID: 25848029]. Pyrococcus species appear to have three different forms of this enzyme, so it is unclear whether all members of this family have the same function. This family is a member of the haloacid dehalogenase (HAD) superfamily of hydrolases which are characterised by three conserved sequence motifs. By virtue of an alpha helical domain in-between the first and second conserved motif, this family is a member of subfamily IA [PMID: 7966317].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016787 hydrolase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.