Meiotic recombinase Dmc1 (IPR011940)

Short name: DMC1_rcmbase

Overlapping homologous superfamilies

Family relationships


This entry describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (IPR011938) and RadB (IPR011939) and bacterial RecA. It has been characterised for human as a recombinase active only in meiosis [PMID: 15164066].

GO terms

Biological Process

GO:0007131 reciprocal meiotic recombination

Molecular Function

GO:0005524 ATP binding
GO:0003677 DNA binding
GO:0008094 DNA-dependent ATPase activity

Cellular Component

GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.