Ribose 5-phosphate isomerase (IPR011860)

Short name: Rib-5-P_Isoase

Overlapping homologous superfamilies

Family relationships


Ribose 5-phosphate isomerase (EC: forms a homodimer and catalyses the interconversion of D-ribose 5-phosphate and D-ribulose 5-phosphate in the non-oxidative branch of the pentose phosphate pathway. This reaction permits the synthesis of ribose from other sugars, as well as the recycling of sugars from nucleotide breakdown. Two unrelated enzymes can catalyse this reaction: RpiA (found in most organisms) and RpiB (found in some bacteria and eukaryotes) [PMID: 14499611].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004751 ribose-5-phosphate isomerase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.