Coenzyme PQQ biosynthesis protein B (IPR011842)

Short name: PQQ_synth_PqqB

Overlapping homologous superfamilies

Family relationships



This entry describes coenzyme PQQ biosynthesis protein B, a gene required for the biosynthesis of pyrrolo-quinoline-quinone (coenzyme PQQ). PQQ is required for some glucose dehydrogenases and alcohol dehydrogenases. Note that this gene appears to be required for PQQ in biosynthesis in Methylobacterium extorquens (under the name pqqG) and in Klebsiella pneumoniae but that the equivalent pqqV in Acinetobacter calcoaceticus is not necessary for heterologous expression of PQQ biosynthesis in Escherichia coli. Based on this latter finding, it is suggested [PMID: 2549866] that PqqB might be a transporter or a PQQ-dependent enzyme rather than a PQQ biosynthesis enzyme [PMID: 2536663].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.