Family

Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family (IPR011613)

Short name: Glyco_hydro_15/PHK

Family relationships

Description

O-Glycosyl hydrolases (EC:3.2.1.) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID: 7624375, PMID: 8535779]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.

This entry represents proteins from Glycoside hydrolase family 15 and Phosphorylase b kinase regulatory chain family.

Glycoside hydrolase family 15 GH15 comprises enzymes with several known activities; glucoamylase (EC:3.2.1.3); alpha-glucosidase (EC:3.2.1.20); glucodextranase (EC:3.2.1.70).

Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation [PMID: 12825073].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam