Family

Type II pantothenate kinase, bacterial (IPR011602)

Short name: Type_II_PanK_bac

Family relationships

Description

Pantothenate kinase (PanK or CoaA) catalyses the first step of the universal five step coenzyme A (CoA) biosynthesis pathway. Three distinct types of pantothenate kinase enzymes have been identified: type I PanK enzymes are typified by the E. coli CoaA protein; type II enzymes are primarily found in eukaryotic organisms; whilst type III enzymes have a wider phylogenic distribution and are not feedback inhibited by CoA [PMID: 8186650].

This entry represents PanK type II family members from bacteria, which may have originated from the eukaryotic form by lateral transfer.

GO terms

Biological Process

GO:0015937 coenzyme A biosynthetic process

Molecular Function

GO:0005524 ATP binding
GO:0004594 pantothenate kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
HAMAP
PIRSF