Telomeric single stranded DNA binding POT1/Cdc13 (IPR011564)

Short name: Telomer_end-bd_POT1/Cdc13

Overlapping homologous superfamilies

Domain relationships



This domain binds single stranded telomeric DNA and adopts an OB fold [PMID: 11935027]. It includes the proteins POT1 and Cdc13 which have been shown to regulate telomere length, replication and capping [PMID: 11230149, PMID: 18066078, PMID: 16943437]. POT1 is one component of the shelterin complex that protects telomere-ends from attack by DNA-repair mechanisms [PMID: 1239117, PMID: 19228335].

GO terms

Biological Process

GO:0000723 telomere maintenance

Molecular Function

GO:0003677 DNA binding

Cellular Component

GO:0000784 nuclear chromosome, telomeric region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.