Ferredoxin 2Fe-2S type, proteobacteria (IPR011536)

Short name: Fdx_isc

Overlapping homologous superfamilies

Family relationships

  • Adrenodoxin (IPR001055)
    • Ferredoxin 2Fe-2S type, proteobacteria (IPR011536)


At least three types of Fe-S cluster-biosynthesis systems are known: NIF, ISC and SUF [PMID: 15952888]. This family consists of proteobacterial ferredoxins associated with and essential to the ISC (iron-sulfur cluster) system of 2Fe-2S cluster assembly [PMID: 11551196]. This family is closely related to (but excludes) eukaryotic (mitochondrial) adrenodoxins, which are ferredoxins involved in electron transfer to P450 cytochromes.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0051537 2 iron, 2 sulfur cluster binding
GO:0009055 electron transfer activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.