Fibrillin/Microneme protein4 (IPR011398)

Short name: FBN/EtMIC4

Family relationships



This family includes fibrillin-1, 2 and 3. Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-containing microfibrils provide long-term force bearing structural support [PMID: 14962672].

This entry also includes microneme protein 4 (EtMIC4) from Eimeria tenella. EtMIC4 is a transmembrane protein that has multiple thrombospondin type I domains and calcium-binding epidermal growth factor-like domains in its extracellular domain [PMID: 11566298]. It forms a complex with EtMIC5 that binds target host cells [PMID: 17426025].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0005509 calcium ion binding
GO:0005201 extracellular matrix structural constituent

Cellular Component

GO:0005578 proteinaceous extracellular matrix

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.