Malate dehydrogenase, type 3 (IPR011275)

Short name: Malate_DH_type3

Overlapping homologous superfamilies

Family relationships


This entry contains bacterial and archaeal malate dehydrogenases, which convert malate into oxaloacetate in the citric acid cycle. The critical residues which discriminate malate dehydrogenase from lactate dehydrogenase have been characterised [PMID: 11021970], and have been used to determine members of this group.

This entry also includes eukaryotic L-lactate dehydrogenase, which is involved in the pyruvate fermentation to lactate pathway [PMID: 8577343].

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.