D-alanine--D-alanine ligase, C-terminal (IPR011095)

Short name: Dala_Dala_lig_C

Overlapping homologous superfamilies


Domain relationships

  • ATP-grasp fold (IPR011761)
    • D-alanine--D-alanine ligase, C-terminal (IPR011095)


This entry represents the C-terminal, catalytic domain of the D-alanine--D-alanine ligase enzyme EC: D-Alanine is one of the central molecules of the cross-linking step of peptidoglycan assembly. There are three enzymes involved in the D-alanine branch of peptidoglycan biosynthesis: the pyridoxal phosphate-dependent D-alanine racemase (Alr), the ATP-dependent D-alanine: D-alanine ligase (Ddl), and the ATP-dependent D-alanine:D-alanine-adding enzyme (MurF) [PMID: 12499203].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008716 D-alanine-D-alanine ligase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.