tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal (IPR011063)

Short name: TilS/TtcA_N

Overlapping homologous superfamilies

Domain relationships


The structure of tRNA(Ile)-lysidine synthetase consists of an N-terminal dinucleotide-binding fold domain (NTD), and a C-terminal globular domain (CTD). The structure of the NTD closely resembles that of a P-loop "N-type" ATP pyrophosphatase [PMID: 15894617]. tRNA(Ile)-lysidine and 2-thiocytidine synthase both belong to the PP-loop superfamily [PMID: 7731953].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.