Pathways & interactions
Quinoprotein alcohol dehydrogenase-like superfamily (IPR011047)
Short name: Quinoprotein_ADH-like_supfam
- PQQ-dependent membrane bound dehydrogenase (IPR017511)
- PQQ-dependent dehydrogenase, methanol/ethanol family (IPR017512)
- Outer membrane protein assembly factor BamB (IPR017687)
- ER membrane protein complex subunit 1 (IPR026895)
- Acido-empty-quinoprotein group A (IPR030939)
- PQQ-dependent type I alcohol dehydrogenase (IPR034119)
Quinoprotein alcohol dehydrogenases are a family of proteins found in methylotrophic or autotrophic bacteria. These quinoproteins use pyrroloquinoline quinone as their prosthetic group. There are three types of alcohol dehydrogenases: type I includes methanol dehydrogenase and ethanol dehydrogenase, type II includes soluble quinohaemoprotein with a C-terminal containing haem C, and type III includes quinoprotein alcohol dehydrogenase with a C-terminal cytochrome C domain [PMID: 11761326]. These quinoproteins contain an 8-bladed beta-propeller motif, which is present in the N-terminal domain of quinoprotein alcohol dehydrogenase, ethanol dehydrogenase, and the heavy chain (alpha subunit) of methanol dehydrogenase (EC:188.8.131.52) [PMID: 11714714, PMID: 12686116, PMID: 12686102].
This entry represents quinoprotein alcohol dehydrogenases as well as some other proteins that share a similar structure, including WD repeat-containing protein and echinoderm microtubule-associated protein-like proteins.
- SSF50998 (SSF50998)