Homologous Superfamily

Transcription Factor IIF, Rap30/Rap74, interaction (IPR011039)

Short name: TFIIF_interaction

Overlapping entries


Transcription factor IIF (TFIIF), which is essential for eukaryotic transcription by RNA polymerase II. (PolII), consists of a heterodimer of Rap30 (beta) (IPR003196) and Rap74 (alpha) (IPR008851) subunits [PMID: 11183778]. Rap30 and Rap74 have multiple domains that bind to PolII, TFIIB, TAF250 and DNA in interactions that are essential for transcription initiation and elongation. The N-terminal interactions domains of Rap30 and Rap74 are responsible for establishing the dimer interface between the two subunits, this interface being important for TFIIF function [PMID: 12354769].

GO terms

Biological Process

GO:0006367 transcription initiation from RNA polymerase II promoter

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.