Pathways & interactions
Literature: DNA breaking-rejoining enzyme, catalytic core (IPR011010)
References used in this entry
The following publications were referred to in the abstract:
Phage integrases: biology and applications.
Groth AC, Calos MP.
J. Mol. Biol. 335 667-78 2004
PMID: 14687564 Related citations
Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA.
Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG.
Science 279 1504-13 1998
PMID: 9488644 Related citations
Conservation of structure and function among tyrosine recombinases: homology-based modeling of the lambda integrase core-binding domain.
Swalla BM, Gumport RI, Gardner JF.
Nucleic Acids Res. 31 805-18 2003
PMID: 12560475 Related citations
The following publications were not referred to in the abstract, but provide useful additional information:
Synapsis of loxP sites by Cre recombinase.
Ghosh K, Guo F, Van Duyne GD.
J. Biol. Chem. 282 24004-16 2007
PMID: 17573343 Related citations
A structural basis for allosteric control of DNA recombination by lambda integrase.
Biswas T, Aihara H, Radman-Livaja M, Filman D, Landy A, Ellenberger T.
Nature 435 1059-66 2005
PMID: 15973401 Related citations
Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination.
Ghosh K, Lau CK, Guo F, Segall AM, Van Duyne GD.
J. Biol. Chem. 280 8290-9 2005
PMID: 15591069 Related citations
Structures of three classes of anticancer agents bound to the human topoisomerase I-DNA covalent complex.
Staker BL, Feese MD, Cushman M, Pommier Y, Zembower D, Stewart L, Burgin AB.
J. Med. Chem. 48 2336-45 2005
PMID: 15801827 Related citations
Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysis.
Ioanoviciu A, Antony S, Pommier Y, Staker BL, Stewart L, Cushman M.
J. Med. Chem. 48 4803-14 2005
PMID: 16033260 Related citations