Family

[NiFe]-hydrogenase maturation factor HyaE (IPR010893)

Short name: NiFe-hyd_mat_HyaE

Overlapping homologous superfamilies

Family relationships

None.

Description

This family contains bacterial hydrogenase-1 expression proteins approximately 120 residues long. This includes the Escherichia coli protein HyaE, and the homologous proteins HoxO of Ralstonia eutropha (Alcaligenes eutrophus) and HupG of Rhizobium leguminosarum. Deletion of the hoxO gene in R. eutropha led to complete loss of the uptake [NiFe] hydrogenase activity, suggesting that it has a critical role in hydrogenase assembly [PMID: 12914940].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PIRSF
CDD
Pfam