Family

Cyclin-dependent kinase inhibitor 2A (IPR010868)

Short name: Cyclin_kinase-Inhib_2A

Family relationships

None.

Description

This entry represents the cyclin-dependent kinase inhibitor 2A, which seems to be restricted to mammals. This is a tumour-suppressor protein that has been shown to inhibit the growth of human tumour cells lacking functional p53 by inducing a transient G2 arrest and subsequently apoptosis [PMID: 12660818].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam