Family

Zona-pellucida-binding (IPR010857)

Short name: Sp38-bd

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This family contains a number of zona-pellucida-binding proteins that seem to be restricted to mammals. These are sperm proteins that bind to the 90 kDa family of zona pellucida glycoproteins in a calcium-dependent manner [PMID: 7729589]. These represent some of the specific molecules that mediate the first steps of gamete interaction, allowing fertilisation to occur [PMID: 9378618].

GO terms

Biological Process

GO:0007339 binding of sperm to zona pellucida

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PANTHER