Domain

Occludin homology domain (IPR010844)

Short name: Occludin_ELL

Domain relationships

None.

Description

This represents a conserved region approximately 100 residues long within eukaryotic occludin proteins and the RNA polymerase II elongation factor ELL. Occludin is an integral membrane protein that localises to tight junctions [PMID: 8276896], while ELL is an elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA [PMID: 8596958]. This shared domain is thought to mediate protein interactions [PMID: 8276896].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam