Family

Ecd family (IPR010770)

Short name: Ecd

Family relationships

None.

Description

This entry represents Ecd (ecdysoneless) family. Drosophila ecd mutants display reduced steroid titers during larval development [PMID: 16592466]. Mammalian Ecd (also known as SGT1 and hEcd in humans) has been shown to stimulate cell proliferation by interacting with the Retinoblastoma (Rb) proteins [PMID: 19640839]. Ecd proteins may be involved in pre-mRNA splicing [PMID: 24722212].

Overexpression of Ecd has been linked to cancer progression [PMID: 22270930, PMID: 22977192].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam