Family

Group XII secretory phospholipase A2 precursor (IPR010711)

Short name: PLA2G12

Family relationships

None.

Description

This family consists of several group XII secretory phospholipase A2 precursor (PLA2G12) (EC:3.1.1.4) proteins. Group XII and group V PLA(2)s are thought to participate in helper T cell immune response through release of immediate second signals and generation of downstream eicosanoids [PMID: 11278438].

GO terms

Biological Process

GO:0016042 lipid catabolic process

Molecular Function

GO:0005509 calcium ion binding
GO:0004623 phospholipase A2 activity

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PANTHER
Pfam