RNA polymerase II transcription factor SIII, subunit A (IPR010684)

Short name: RNA_pol_II_trans_fac_SIII_A

Overlapping homologous superfamilies


Family relationships



This family represents a conserved region within RNA polymerase II transcription factor SIII (Elongin) subunit A. In mammals, the Elongin complex activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin is a heterotrimer composed of A, B, and C subunits of 110, 18, and 15 kilodaltons, respectively. Subunit A has been shown to function as the transcriptionally active component of Elongin [PMID: 7660129].

GO terms

Biological Process

GO:0006357 regulation of transcription by RNA polymerase II

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0070449 elongin complex
GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.