Protein of unknown function DUF1232 (IPR010652)

Short name: DUF1232

Family relationships


This entry includes RNF170 from eukaryotes and some uncharacterised proteins from bacteria and archaea. RNF170 is an E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway [PMID: 21610068].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.