Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase (IPR010635)

Short name: Heparan_SO4-6-sulfoTrfase

Overlapping homologous superfamilies


Family relationships

  • Sulfotransferase (IPR005331)
    • Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase (IPR010635)


This family consists of several heparan sulphate 6-sulphotransferase (HS6ST) proteins. Heparan sulphate 6-O-sulphotransferase (HS6ST) catalyses the transfer of sulphate from adenosine 3'-phosphate, 5'-phosphosulphate to the 6th position of the N-sulphoglucosamine residue in heparan sulphate [PMID: 12492399]. This entry also includes protein-tyrosine sulfotransferase, which catalyses the O-sulfation of tyrosine residues within acidic motifs of polypeptides [PMID: 19666544].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008146 sulfotransferase activity

Cellular Component

GO:0016021 integral component of membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.