Family

Haem-binding HasA (IPR010495)

Short name: HasA_haem-bd

Family relationships

None.

Description

Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted haemophore that has the ability to obtain iron from haemoglobin. Once bound to HasA, the haem is shuttled to the receptor HasR, which releases the haem into the bacterium [PMID: 10360351].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF