Alpha-2-macroglobulin RAP, C-terminal (IPR010483)

Short name: Alpha_2_MRAP_C

Overlapping homologous superfamilies


Domain relationships



The alpha-2-macroglobulin receptor-associated protein (RAP) is a intracellular glycoprotein that binds to the 2-macroglobulin receptor and other members of the low density lipoprotein receptor family. The protein inhibits binding of all currently known ligands of these receptors [PMID: 9207124]. Two different studies have provided conflicting domain boundaries.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0008201 heparin binding
GO:0050750 low-density lipoprotein particle receptor binding

Cellular Component

GO:0005783 endoplasmic reticulum

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.