Bor (IPR010438)

Short name: Lambda_Bor

Overlapping homologous superfamilies


Family relationships



This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the E. coli host cell in animal serum. This property is a well known bacterial virulence determinant. Indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis [PMID: 2144037].

Bor and Iss have been shown to be present on the outer membrane of E. coli, where they may be recognised by the host's immune system [PMID: 17309614].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0009279 cell outer membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.