tRNA-hydroxylase MiaE (IPR010386)

Short name: tRNA-Hydrxlase_MiaE

Family relationships



This family consists of several bacterial tRNA-(MSIO[6]A)-hydroxylase (MiaE) proteins. The modified nucleoside 2-methylthio-N-6-isopentenyl adenosine (ms2i6A) is present at position 37 (3' of the anticodon) of tRNAs that read codons beginning with U except tRNA(I,V Ser) in Escherichia coli. Salmonella typhimurium 2-methylthio-cis-ribozeatin (ms2io6A) is found in tRNA, probably in the corresponding species that have ms2i6A in E. coli. The miaE gene is absent in E. coli, a finding consistent with the absence of the hydroxylated derivative of ms2i6A in this species [PMID: 8253666].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.