mRNA-decapping enzyme subunit 1 (IPR010334)

Short name: Dcp1

Family relationships



An essential step in mRNA turnover is decapping. In yeast, two proteins have been identified that are essential for decapping, Dcp1 (this family) and Dcp2. Dcp1 is a coactivator that binds to the decapping enzyme Dcp2 and forms a decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation [PMID: 16341225]. Yeast Dcp1 interact directly with Dcp2, however, the Dcp1-Dcp2 interaction is promoted by an additional factor, EDC4 [PMID: 24510189].

GO terms

Biological Process

GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0043085 positive regulation of catalytic activity

Molecular Function

GO:0008047 enzyme activator activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.