Cysteine dioxygenase type I (IPR010300)

Short name: CDO_1

Overlapping homologous superfamilies

Family relationships



Cysteine dioxygenase (CDO) plays an important role in the homeostatic regulation of steady-state cysteine levels and provides important oxidized metabolites of cysteine such as sulfate and taurine. It converts cysteine to cysteinesulphinic acid and is the rate-limiting step in sulphate production [PMID: 16855246].

This entry also includes a cysteine dioxygenase homologue from Pseudomonas aeruginosa known as p3MDO. It functions as a 3-mercaptopropionate dioxygenase that catalyses the dioxygenation of 3-MPA to 3-sulfinopropionic acid (3-SPA) [PMID: 26272617]. 3-Mercaptopropionic acid (3-MPA) is a structural analogue of cysteine.

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0005506 iron ion binding
GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.