DNA-binding transcriptional activator AlpA (IPR010260)

Short name: AlpA

Overlapping homologous superfamilies


Family relationships



This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppresses two phenotypes of a delta lon protease mutant, overproduction of capsular polysaccharide and sensitivity to UV light. AlpA acts as a transcriptional regulator of the slpA gene; activation of slpA transcription is necessary to suppress these phenotypes [PMID: 7511582]. Several of the sequences in this family are thought to be DNA-binding proteins.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.