Family

DNA-binding transcriptional activator AlpA (IPR010260)

Short name: AlpA

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppresses two phenotypes of a delta lon protease mutant, overproduction of capsular polysaccharide and sensitivity to UV light. AlpA acts as a transcriptional regulator of the slpA gene; activation of slpA transcription is necessary to suppress these phenotypes [PMID: 7511582]. Several of the sequences in this family are thought to be DNA-binding proteins.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam