NADH-quinone oxidoreductase, chain I (IPR010226)

Short name: NADH_quinone_OxRdtase_chainI

Overlapping homologous superfamilies


Family relationships


This entry represents the I subunit (one of 14 subunits, A to N) of the NADH-quinone oxidoreductase complex I (EC: which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This family does not contain 'I' subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes.

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0051539 4 iron, 4 sulfur cluster binding
GO:0016651 oxidoreductase activity, acting on NAD(P)H

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.