Family

Phosphoribosylformylglycinamidine synthase, FGAM (IPR010141)

Short name: FGAM_synthase

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents a single-molecule form of phosphoribosylformylglycinamidine synthase, also called FGAM synthase, an enzyme of purine de novo biosynthesis, which represent a second clade of the enzymes found in Clostridia, Bifidobacteria and Streptococcus species. This enzyme performs the fourth step in IMP biosynthesis (the precursor of all purines) from PRPP.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs