Family

Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (IPR010137)

Short name: Lipid_A_LpxA

Family relationships

None.

Description

This entry describes LpxA, an enzyme for the biosynthesis of lipid A, a component of lipopolysaccharide (LPS) in the outer membrane outer leaflet of most Gram-negative bacteria. Some differences are found between lipid A of different species, but this protein represents the first step (from UDP-N-acetyl-D-glucosamine) and appears to be conserved in function. Proteins from this family contain many copies of the bacterial transferase hexapeptide repeat.

GO terms

Biological Process

GO:0008610 lipid biosynthetic process

Molecular Function

GO:0008780 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
PIRSF
HAMAP