Family

LPPG:Fo 2-phospho-L-lactate transferase (IPR010115)

Short name: LPPG-Fo_P-lactate_Trfase

Family relationships

Description

This entry contains LPPG:Fo 2-phospho-L-lactate transferase (CofD). CofD catalyses the fourth step in the biosynthesis of coenzyme F420, which is the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) and GMP. F420 is a flavin derivative found in methanogens, Mycobacteria, and several other lineages. This enzyme is characterised so far in Methanocaldococcus jannaschii (Methanococcus jannaschii) [PMID: 11888293] but appears restricted to F420-containing species and is predicted to carry out the same function in these other species.

GO terms

Biological Process

GO:0051188 cofactor biosynthetic process

Molecular Function

GO:0000287 magnesium ion binding
GO:0016780 phosphotransferase activity, for other substituted phosphate groups

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
HAMAP