Family

Phosphoribosylformylglycinamidine synthase (IPR010073)

Short name: PRibForGlyAmidine_synth

Family relationships

None.

Description

This entry represents a single-molecule form of phosphoribosylformylglycinamidine synthase, also called FGAM synthase, an enzyme of purine de novo biosynthesis. This form is found mostly in eukaryotes and proteobacteria. In Bacillus subtilis PurL (FGAM synthase II) and PurQ (FGAM synthase I) perform the equivalent function; the unrelated small protein PurS is also required and may be a third subunit [PMID: 10784038].

GO terms

Biological Process

GO:0006189 'de novo' IMP biosynthetic process

Molecular Function

GO:0004642 phosphoribosylformylglycinamidine synthase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
HAMAP
TIGRFAMs