Family

Uroplakin II (IPR009952)

Short name: Uroplakin_II

Family relationships

None.

Description

This family contains uroplakin II, which is approximately 180 residues long and seems to be restricted to mammals. Uroplakin II is an integral membrane protein, and is one of the components of the apical plaques of mammalian urothelium formed by the asymmetric unit membrane - this is believed to play a role in strengthening the urothelial apical surface to prevent the cells from rupturing during bladder distension [PMID: 8175808].

GO terms

Biological Process

GO:0061024 membrane organization

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0030176 integral component of endoplasmic reticulum membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF
ProDom
PANTHER