Family

Putative Actinobacterial Holin-X, holin superfamily III (IPR009937)

Short name: Phage_holin_3_6

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam