Apopolysialoglycoprotein (IPR009900)

Short name: PSGP


This entry represents a series of 13 residue repeats found in the apopolysialoglycoprotein of Oncorhynchus mykiss (Rainbow trout) and Oncorhynchus masou (Cherry salmon). Polysialoglycoprotein (PSGP) of unfertilised eggs of rainbow trout consists of tandem repeats of a glycotridecapeptide, Asp-Asp-Ala-Thr*-Ser*-Glu-Ala-Ala-Thr*-Gly-Pro-Ser- Gly (* denotes the attachment site of a polysialoglycan chain). In response to egg activation, PSGP is discharged by exocytosis into the space between the vitelline envelope and the plasma membrane, i.e. the perivitelline space, where the 200kDa PSGP molecules undergo rapid and dramatic depolymerisation by proteolysis into glycotridecapeptides [PMID: 3182867].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.