Family

Inner membrane protein YgfX (IPR009883)

Short name: YgfX

Family relationships

None.

Description

This family includes bacterial proteins including the probable inner membrane protein YgfX from Escherichia coli (formerly known as CptA). This had been thought to be a toxin, but it has no effect on cell growth [PMID: 23657679]. It has been shown to interacts with the cytoskeletal proteins FtsZ and MreB and to inhibit FtsZ GTP-dependent and MreB ATP-dependent polymerization [PMID: 22239607]. In Serratia strains deficient in sdhE-ygfX, YgfX restores production of the antibiotic prodigiosin [PMID: 22474332].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
PIRSF
Pfam