Family

Type III secretion protein, LcrG (IPR009863)

Short name: T3SS_LcrG_PcrG

Family relationships

None.

Description

LcrG is found in type III secretion operons, along with LcrR, H and V. LcrG is a negative regulator for secretion of Yersinia outer-membrane proteins (Yops) by blocking the secretion apparatus from the inner membrane [PMID: 9484897, PMID: 19109068]. Also known as PcrG in Pseudomonas, the protein is believed to make a 1:1 complex with PcrV (LcrV) [PMID: 14565848]. Mutations in LcrG cause premature secretion of effector proteins into the medium [PMID: 11443094].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom
TIGRFAMs