Domain

Involucrin 2 (IPR009733)

Short name: Involucrin2

Domain relationships

None.

Description

This domain represents a conserved region approximately 60 residues long, multiple copies of which are found within eukaryotic involucrin, and which is rich in glutamine and glutamic acid residues. Involucrin forms part of the insoluble cornified cell envelope (a specialised protective barrier) of stratified squamous epithelia [PMID: 12210515].

GO terms

Biological Process

GO:0030216 keratinocyte differentiation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0001533 cornified envelope

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam