Rex DNA-binding, C-terminal domain (IPR009718)

Short name: Rex_DNA-bd_C_dom

Overlapping homologous superfamilies

Domain relationships



This entry represents the C terminus (approximately 30 residues) of a number of Rex proteins. These are redox-sensing repressors that appear to be widespread among Gram-positive bacteria [PMID: 12970197]. They modulate transcription in response to changes in cellular NADH/NAD(+) redox state. Rex is predicted to include a pyridine nucleotide-binding domain (Rossmann fold), and residues that might play key structural and nucleotide binding roles are highly conserved.

GO terms

Biological Process

GO:0045892 negative regulation of transcription, DNA-templated
GO:0051775 response to redox state

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005737 cytoplasm

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.