Centromere protein R (IPR009601)

Short name: CENP-R

Family relationships



Centromere protein R (CENP-R, also known as NRIF3) is a transcription co-regulator that can have both co-activator and co-repressor functions [PMID: 10490654, PMID: 11713274]. It is involved in the co-activation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion [PMID: 12244126, PMID: 15254226]. It is a probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation [PMID: 16622419].

GO terms

Biological Process

GO:0034080 CENP-A containing nucleosome assembly
GO:0006355 regulation of transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.